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The TRIPOD-LLM reporting guideline for studies using large language models
| Reporting guideline provided for? (i.e. exactly what the authors state in the paper) |
Reporting of studies that are developing, tuning, prompt engineering or evaluating a large language model (LLM). |
| Full bibliographic reference | Gallifant J, Afshar M, Ameen S, Aphinyanaphongs Y, Chen S, Cacciamani G, Demner-Fushman D, Dligach D, Daneshjou R, Fernandes C, Hansen LH, Landman A, Lehmann L, McCoy LG, Miller T, Moreno A, Munch N, Restrepo D, Savova G, Umeton R, Gichoya JW, Collins GS, Moons KGM, Celi LA, Bitterman DS. The TRIPOD-LLM reporting guideline for studies using large language models. Nat Med. 2025. |
| Language | English |
| PubMed ID | 39779929 |
| Relevant URLs (full-text if available) |
Read the full-text of the TRIPOD-LLM guideline. |
| Relevant more generic / specialised reporting guidelines (i.e. main generic guideline or extension to a generic guideline) |
Generic TRIPOD+AI Statement: Collins GS, Moons KGM, Dhiman P, Riley RD, Beam AL, Van Calster B, Ghassemi M, Liu X, Reitsma JB, van Smeden M, Boulesteix AL, Camaradou JC, Celi LA, Denaxas S, Denniston AK, Glocker B, Golub RM, Harvey H, Heinze G, Hoffman MM, Kengne AP, Lam E, Lee N, Loder EW, Maier-Hein L, Mateen BA, McCradden MD, Oakden-Rayner L, Ordish J, Parnell R, Rose S, Singh K, Wynants L, Logullo P. TRIPOD+AI statement: updated guidance for reporting clinical prediction models that use regression or machine learning methods. BMJ. 2024;385:e078378. PMID: 38626948 Specialised TRIPOD-SRMA: Snell KIE, Levis B, Damen JAA, Dhiman P, Debray TPA, Hooft L, Reitsma JB, Moons KGM, Collins GS, Riley RD. Transparent reporting of multivariable prediction models for individual prognosis or diagnosis: checklist for systematic reviews and meta-analyses (TRIPOD-SRMA). BMJ. 2023;381:e073538. PMID: 37137496 TRIPOD-Cluster: Debray TPA, Collins GS, Riley RD, Snell KIE, Van Calster B, Reitsma JB, Moons KGM. Transparent reporting of multivariable prediction models developed or validated using clustered data: TRIPOD-Cluster checklist. BMJ. 2023;380:e071018. PMID: 36750242 |
| Reporting guideline website URL | https://tripod-llm.vercel.app/ |
| Reporting guideline acronym | TRIPOD-LLM |
| Study design | Artificial intelligence/Machine learning studies |
| Applies to the whole report or to individual sections of the report? | Whole report |
| Other | The guideline includes a separate checklist for journal or conference abstracts of LLM-based studies (TRIPOD-LLM for abstracts). |
| Record last updated on | January 10, 2025 |