Enhancing the QUAlity and Transparency Of health Research

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07/12/2023 Consensus Statement for Protocols of Factorial Randomized Trials: Extension of the SPIRIT 2013 Statement 24/10/2023 Enhancing quality and impact of early phase dose-finding clinical trial protocols: SPIRIT Dose-finding Extension (SPIRIT-DEFINE) guidance 04/01/2023 Guidelines for Reporting Outcomes in Trial Protocols: The SPIRIT-Outcomes 2022 Extension 01/10/2021 Guidelines for cellular and molecular pathology content in clinical trial protocols: the SPIRIT-Path extension 07/02/2018 Guidelines for Inclusion of Patient-Reported Outcomes in Clinical Trial Protocols: The SPIRIT-PRO Extension 14/05/2017 SPIRIT 2013 Statement: Defining standard protocol items for clinical trials 07/11/2016 Consensus on Exercise Reporting Template (CERT): Modified Delphi Study 18/03/2016 DELTA2 guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial

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