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TRIPOD + AI statement: updated guidance for reporting clinical prediction models that use regression or machine learning methods
| Reporting guideline provided for? (i.e. exactly what the authors state in the paper) |
Reporting of studies that develop a prediction model or evaluate its performance. |
| Full bibliographic reference | Collins GS, Moons KGM, Dhiman P, Riley RD, Beam AL, Van Calster B, Ghassemi M, Liu X, Reitsma JB, van Smeden M, Boulesteix AL, Camaradou JC, Celi LA, Denaxas S, Denniston AK, Glocker B, Golub RM, Harvey H, Heinze G, Hoffman MM, Kengne AP, Lam E, Lee N, Loder EW, Maier-Hein L, Mateen BA, McCradden MD, Oakden-Rayner L, Ordish J, Parnell R, Rose S, Singh K, Wynants L, Logullo P. TRIPOD+AI statement: updated guidance for reporting clinical prediction models that use regression or machine learning methods. BMJ. 2024;385:e078378. |
| Language | English |
| PubMed ID | 38626948 |
| Relevant URLs (full-text if available) |
Read the full-text of TRIPOD+AI. The TRIPOD+AI checklist (PDF) is available in Supplementary Table 2. The TRIPOD+AI Expanded Checklist (PDF) (Explanation & Elaboration Light) is available in Supplementary Table 1. The TRIPOD+AI for Abstracts checklist is available in Table 3 of the statement paper. |
| Explanation and elaboration papers | Please continue to use the TRIPOD 2015 E&E paper until the TRIPOD+AI E&E paper is available: Moons KG, Altman DG, Reitsma JB, Ioannidis JP, Macaskill P, Steyerberg EW, Vickers AJ, Ransohoff DF, Collins GS. Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis (TRIPOD): Explanation and Elaboration. Ann Intern Med. 2015;162(1):W1-W73. PMID: 25560730 |
| Availability in additional languages | TRIPOD 2015 The TRIPOD 2015 statement and reporting checklist are also available in the following languages: TRIPOD 2015 Checklist (Chinese) Word TRIPOD 2015 E&E (Japanese) Word TRIPOD 2015 Checklist (Japanese) Word | PDF TRIPOD 2015 E&E (Russian) PDF |
| Relevant more generic / specialised reporting guidelines (i.e. main generic guideline or extension to a generic guideline) |
Specialised TRIPOD-SRMA: Snell KIE, Levis B, Damen JAA, Dhiman P, Debray TPA, Hooft L, Reitsma JB, Moons KGM, Collins GS, Riley RD. Transparent reporting of multivariable prediction models for individual prognosis or diagnosis: checklist for systematic reviews and meta-analyses (TRIPOD-SRMA). BMJ. 2023;381:e073538. PMID: 37137496 TRIPOD-Cluster: Debray TPA, Collins GS, Riley RD, Snell KIE, Van Calster B, Reitsma JB, Moons KGM. Transparent reporting of multivariable prediction models developed or validated using clustered data: TRIPOD-Cluster checklist. BMJ. 2023;380:e071018. PMID: 36750242 TRIPOD-LLM: Gallifant J, Afshar M, Ameen S, Aphinyanaphongs Y, Chen S, Cacciamani G, Demner-Fushman D, Dligach D, Daneshjou R, Fernandes C, Hansen LH, Landman A, Lehmann L, McCoy LG, Miller T, Moreno A, Munch N, Restrepo D, Savova G, Umeton R, Gichoya JW, Collins GS, Moons KGM, Celi LA, Bitterman DS. The TRIPOD-LLM reporting guideline for studies using large language models. Nat Med. 2025. PMID: 39779929 |
| Reporting guideline website URL | http://www.tripod-statement.org/ |
| Reporting guideline acronym | TRIPOD+AI |
| Study design | Artificial intelligence/Machine learning studies, Diagnostic and prognostic studies, Observational studies |
| Applies to the whole report or to individual sections of the report? | Whole report |
| Previous versions of this guideline / Guideline history | TRIPOD 2015 Collins GS, Reitsma JB, Altman DG, Moons KG. Transparent reporting of a multivariable prediction model for individual prognosis or diagnosis (TRIPOD): The TRIPOD statement. Ann Intern Med. 2015;162(1):55-63. PMID: 25560714 Br J Cancer. 2015 Jan 6. PMID: 25562432 Circulation. 2015 Jan 13;131(2):211-9. PMID: 25561516 BMJ 2015; 350:g7594. PMID: 25569120 J Clin Epidemiol. 2015 Feb;68(2):134-43. PMID: 25579640 Eur Urol. 2014 Dec 9. PMID: 25572824 BMC Med. 2015 Jan 6;13(1):1. PMID: 25563062 Eur J Clin Invest. 2015;45(2):204-214. PMID: 25623047 Br J Surg. 2015;102(3):148-158. PMID: 25627261 BJOG. 2015;122(3):434-443. PMID: 25623578 Diabet Med. 2015;32(2):146-154. PMID: 25600898 TRIPOD for Abstracts Heus P, Reitsma JB, Collins GS, Damen JAAG, Scholten RJPM, Altman DG, Moons KGM, Hooft L. Transparent Reporting of Multivariable Prediction Models in Journal and Conference Abstracts: TRIPOD for Abstracts. Ann Intern Med. 2020. PMID: 32479165 |
| Other | Read the protocol for the development of TRIPOD+AI. |
| Additional information | An adherence assessment form for measuring adherence to the Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis (TRIPOD) statement has been developed. Heus P, Damen JAAG, Pajouheshnia R, Scholten RJPM, Reitsma JB, Collins GS, Altman DG, Moons KGM, Hooft L.Uniformity in measuring adherence to reporting guidelines: the example of TRIPOD for assessing completeness of reporting of prediction model studies. BMJ Open. 2019;9(4):e025611. PMID: 31023756 The adherence assessment forms are available from: https://www.tripod-statement.org/adherence/ |
| Record last updated on | January 10, 2025 |